Statin use associated with significantly increased risk of diabetes: WHI analysis

The following article was published in Heartwire on JANUARY 9, 2012 by Michael O’Riordan

Boston, MA - Statin use in postmenopausal women is associated with a significantly increased risk of diabetes mellitus, research shows. New data from the Women’s Health Initiative (WHI) hint that the risk of diabetes is higher than suggested by previous studies, with investigators reporting a . . . → Read More: Statin use associated with significantly increased risk of diabetes: WHI analysis

Stem Cell therapy may reverse Type 1 Diabetes

January 10, 2012 — An immune regulator from healthy cord blood stem cells (CB-SCs) can “educate” the T cells of a person with type 1 diabetes (T1D), enabling the pancreas to produce insulin, according to a report published online January 10, 2012, in BMC Medicine.

Yong Zhao, MD, PhD, from the University of Illinois at Chicago, and . . . → Read More: Stem Cell therapy may reverse Type 1 Diabetes

Low Cholesterol in Elderly Doubles Risk of Early Death

Study Finds that Low Cholesterol in Elderly Doubles Risk of Early Death

Study finds that elderly with cholesterol less that 189 had a double risk of dying.

Physicians were informed to consider very low levels of cholesterol as potential warning signs of a serious disease or as signals of rapidly declining health.

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Breakthrough in genetic and cellular therapy in cancer

There is a recent breakthrough in genetic and cell therapy that could lead to a dramatic difference in the management of cancers; A team from University of Pennsylvania have been able to genetically modify the T cells of patients with B cell Chronic Lymphocytic Leukemia with a “chimeric antigen receptor” CAR targeting a CD . . . → Read More: Breakthrough in genetic and cellular therapy in cancer

The Central Dogma been challenged

We spoke of epigenetics in the context that the Central Dogma of gene transcription and translation is not a simple linear relation but is part of a complex cellular network system. The old theory of genetic determinism based sole on the sequence of gene determining the coding of genetic messages to form amino acids . . . → Read More: The Central Dogma been challenged

How do we access and arrest poor methylation in the body?

We follow up our discussion on the epigenetic mechanisms that affect gene expression that are asserted by dietary intake, environment toxins and aging. In particular, we mentioned the importance of methylation. Today, I would like to discuss how we could access methylation status in the body and what could be done to prevent hypomethylation. . . . → Read More: How do we access and arrest poor methylation in the body?

Autism – metabolic and nutrition link

A new study published in the June edition of Nutrition and Metabolism this year suggests that children with autism appear to suffer from a significantly higher percentage of metabolic issues compared to average children. Nutritionally, this may be compounded or even initiated by nutritional deficiencies that include low levels of glutathione, biotin, and SAMe, . . . → Read More: Autism – metabolic and nutrition link

Epigenetics – an emerging area of gene research

In biology, and specifically genetics, epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the underlying  DNA sequence – hence the name epi- (Greek: ???- over, above, outer) -genetics. Examples of such changes might be DNA methylation or histone deacetylation, both of which serve to suppress gene expression without altering the sequence of the silenced genes.

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Is this the beginning of the end for dietary supplements?

There is an interesting development lurking in the US regarding the fate of supplements that I thought would be of interest to some of you. I have copied the articles of Warren Matthews, the founder and Chairman of Xtend-Life Natural Products based in New Zealand and Bryon Richards that expressed their concerns and call . . . → Read More: Is this the beginning of the end for dietary supplements?

Acupuncture in Cancer Care

We are pleased have a guest writer Kate Flaherty in today’s blog. Kate is an outreach and awareness coordinator for the Mesothelioma Cancer Alliance in the US.  She is passionate about the role of complementary therapies during comprehensive cancer treatment as well as cancer prevention education.  Kate resides in Upstate New York.

The Benefits . . . → Read More: Acupuncture in Cancer Care

Obesity – genes or diet?

Obesity – nature or nurture….genetic factors are at play in obesity. But you are not doomed by your genetic fate…nutrients have been demonstrated to regulate your fat genes..

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ADAPTIVE THERMOGENESIS – A CAUSE OF RESISTANT WEIGHT CONTROL.

Wonder why it is so difficult for some of your patients to lose weight? There have been many studies that documented substantial reduction in calorie diet intake of some patients and yet their weight remains the same.  We have covered some of the undetected hypothyroidism and leptin resistance as causes. However, there is another . . . → Read More: ADAPTIVE THERMOGENESIS – A CAUSE OF RESISTANT WEIGHT CONTROL.

Surgical management of obesity

In this article we will discuss the surgical treatment of obesity which is the last resort in resistant weight control. This will conclude our thread on Resistant Weight Control. We will be starting a new thread next month and we hope you have enjoyed our series on this global epidemic that is now getting . . . → Read More: Surgical management of obesity

WHI studies in perspective

summaryMHT

First, let’s take a deeper look at the Women’s Health Initiative (WHI) studies that change the medical perspective of menopausal hormone therapy (MHT) and drop the use of hormones significantly.

The menopausal hormone therapy clinical trial had two parts. The first involved 16,608 postmenopausal women with a uterus who took either estrogen plus-progestin therapy . . . → Read More: WHI studies in perspective

Cancer – a nutritional disease?

There is an emerging school of thought that is supported by evidence in research that cancer could be a nutritional disease. Cancer cells are known to plump for aerobic glycolysis and substrate phosphorylation energy system when mitochondria, the power generator of cellular energy are impaired from exotoxins or endotoxins. Normal cells use oxidative phosphorylation . . . → Read More: Cancer – a nutritional disease?

Ergogenic aids in sport performance

There was an enquiry on the affects of combination supplementation of ephedrine compounds (including ma huang, ephedra, and synephrine) and caffeine to enhance sport performance. Here is my response:

Liu et al. (1995) demonstrated that the thermogenic response by ephedrine was mediated by all three beta-adrenoceptors subtyptes and at least 40% of by the . . . → Read More: Ergogenic aids in sport performance

Female athlete triad

 

Female athlete triad in Asia is not well studied although the prevalence is not that low (about 2-4%). Many of us as practitioners could easily miss the diagnosis as the presenting symptoms might be vague and thus a high degree of suspicion is needed.

There was a study in 2009 among 67 elite female athletes . . . → Read More: Female athlete triad