January 10, 2012 — An immune regulator from healthy cord blood stem cells (CB-SCs) can “educate” the T cells of a person with type 1 diabetes (T1D), enabling the pancreas to produce insulin, according to a report published online January 10, 2012, in BMC Medicine.
Yong Zhao, MD, PhD, from the University of Illinois at Chicago, and colleagues base their “stem cell educator therapy” on observations that multipotent stem cells from human cord blood can alter regulatory T cells (Tregs) and islet B cell–specific T-cell clones. The new approach alters autoimmunity both in non-obese diabetic mice and in islet B cells from patients with diabetes.
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